We’re excited to share our latest in-depth report developed in collaboration with AllMyHealth. This guide provides practical insights on how nutrition plays a vital role in managing Duchenne muscular dystrophy (DMD).
Key highlights: understanding DMD and its impact on nutrition, general dietary guidelines for people with DMD, specific nutritional needs for DMD patients, practical advice and meal planning tips (including sample meal plans and recipes).
Available in both text and audio formats - dive in today and share with your community!
In their research, Jaber et al. (2025) discovered that Duchenne Muscular Dystrophy (DMD) involves significant lysosomal damage in muscle cells. They observed an increase in Galectin-3, a marker indicating lysosomal membrane damage, and changes in the number and shape of lysosomes. Current gene therapies, which introduce a shortened form of dystrophin, do not fully address this lysosomal damage.
However, when the researchers combined gene therapy with trehalose, a sugar that protects lysosomes, they saw marked improvements in muscle function and overall muscle health in DMD mice models. This suggests that addressing lysosomal damage could be a key component in developing more effective treatments for DMD. The study indicates that combining gene therapy with treatments targeting lysosomal protection may enhance the therapeutic outcomes for patients with DMD.
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